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51st ERA-EDTA CONGRESS

 

31 May - 3 June 2014 AMSTERDAM
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Discussion forum - 51st ERA-EDTA CONGRESS
    Topic - M) Dialysis. M5) Anaemia in CKD 5D.

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Poster: 482
Visits: 72
Title: TRIFERIC DOES NOT INCREASE PREDIALYSIS HEPCIDIN LEVELS OR IRON SEQUESTRATION: THE PRIME STUDY.
Authors: Gupta Ajay , Vivian Lin, Carrie Guss, Dorine W. Swinkels and Raymond D. Pratt
Centre: Rockwell Medical and Radboud University Medical Center

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TRIFERIC DOES NOT INCREASE PREDIALYSIS HEPCIDIN LEVELS OR IRON SEQUESTRATION: THE PRIME STUDY.

Gupta Ajay
Thread initiator
Subspeciality
Reg: 20/05/2014 14:54:00
Comment# 1
Uremic inflammation increases hepcidin levels leading to iron sequestration in the reticuloendothelial system (RES). Iron sequestration causes, functional iron deficiency (FID) and hyporesponsiveness to ESAs. IV iron can stimulate hepcidin release and worsen iron sequestration and FID.Soluble ferric pyrophosphate citrate (SFP, Triferic) is a small molecular weight investigational parenteral iron salt administered via the dialysate that donates iron directly to transferrin. In a 9 month controlled clinical trial, Triferic administered at each HD did not increase hepcidin-25 compared to placebo.

Comment added on 20/05/2014 14:54:00 
     
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Most viewed poster for this congress
Poster: 7
Visits: 477
Title: SEVERE SYMPTOMATIC ACUTE HYPONATREMIA IN TRAUMATIC BRAIN INJURY RESPONDS VERY RAPIDLY SINGLE 15 MG DOSE OF TOLVAPTAN: A MAYO CLINIC HEALTH SYSTEM HOSPITAL EXPERIENCE - NEED FOR CAUTION WITH TOLVAPTAN IN YOUNGER PATIENTS WITH PRESERVED RENAL FUNCTION
Authors: MACAULAY ONUIGBO ,
Centre: MAYO CLINIC, ROCHESTER & MAYO CLINIC HEALTH SYSTEM, EAU CLAIRE

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Poster: 504
Visits: 165
Title: CAN THE USE OF A NOVEL DIALYSIS BLOODLINE INCREASE HAEMOGLOBIN AND REDUCE ERYTHROPOIETIN DOSES? RESULTS OF A PILOT, CROSSOVER, CLINICAL AUDIT.
Authors: Iain Macdougall , Adam Rumjon,1 Emmanuel Mangahis,1 Leela Goldstein,1 Thomas Ryzlewicz,2 Franz-Ferdinand Becker,2 William Kilgallon.2 1Renal Unit, Kings College Hospital, London, United Kingdom; 2 Oxyless Ltd, Reading, United Kingdom.
Centre: 1Renal Unit, Kings College Hospital, London, United Kingdom; 2 Oxyless Ltd, Reading, United Kingdom.


 








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